Can cisplatin treat breast cancer?
Cisplatin is widely used to treat solid tumors, including breast, testicular, and ovarian cancers [7]. Cisplatin exerts its anticancer effects by inducing DNA double-strand breaks (DSBs) [8, 9]. Despite a consistent initial response, cisplatin treatment results in the development of chemoresistance.
Is cisplatin a strong chemo?
Presently, cisplatin is one of the most powerful chemotherapeutic drugs used for the treatment of ovarian cancer; even though resistance is typical [20]. In ovarian germ cell cancer, the use of cisplatin brings about high response rates [21].
How long can you take cisplatin?
Your course of chemotherapy You have chemotherapy as a course of several sessions (or cycles) of treatment over a few months. Each cycle of cisplatin usually takes 21 days (3 weeks).
When is cisplatin used?
Cisplatin, a chemotherapy drug, is best known for curing testicular cancer. It is also used in the treatment of a wide range of other cancers, including lung, bladder, cervical, and ovarian cancers.
What is the mechanism of action of cisplatin?
The mechanism of action of cisplatin has been associated with ability to crosslink with the urine bases on the DNA to form DNA adducts, preventing repair of the DNA leading to DNA damage and subsequently induces apoptosis within cancer cells.
Do you lose hair with cisplatin?
v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment. v Nausea and vomiting are not unusual but are less common today than in the past because of much improved anti-nausea medications.
How will I feel after cisplatin?
Gastrointestinal – Marked nausea and vomiting occur in almost all patients treated with cisplatin (cisplatin injection) , and are occasionally so severe that the drug must be discontinued. Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours.
When do cisplatin side effects start?
Nausea and vomiting usually begin within 1 to 4 hours after treatment and last up to 24 hours. Various degrees of vomiting, nausea and/or anorexia may persist for up to 1 week after treatment.
Will I lose my hair on cisplatin?
v Hair loss is minimal with cisplatin, but some patients do experience more hair loss than others. Hair growth should return upon completion of treatment.
How bad is cisplatin side effects?
Cisplatin may cause serious kidney problems. Tell you doctor right away if you have blood in urine, change in frequency of urination or amount of urine, difficulty in breathing, drowsiness, increased thirst, loss of appetite, nausea or vomiting, swelling of the feet or lower legs, or weakness.
How bad is cisplatin?
